Saltatory Conduction: Jumping to New Conclusions
نویسندگان
چکیده
منابع مشابه
Jumping to Conclusions
Inspired by the profound effortlessness (but also the substantial carelessness) with which humans seem to draw inferences when given even only partial information, we consider a unified formal framework for computational cognition, placing our emphasis on the existence of naturalistic mechanisms for representing, manipulating, and acquiring knowledge. Through formal results and discussion, we s...
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Almost 90 years ago, Lillie reported that rapid saltatory conduction arose in an iron wire model of nerve impulse propagation when he covered the wire with insulating sections of glass tubing equivalent to myelinated internodes. This led to his suggestion of a similar mechanism explaining rapid conduction in myelinated nerve. In both their evolution and their development, myelinating axons must...
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Voltage-gated sodium channels are concentrated in myelinated nerves at the nodes of Ranvier flanked by paranodal axoglial junctions. Establishment of these essential nodal and paranodal domains is determined by myelin-forming glia, but the mechanisms are not clear. Here, we show that two isoforms of Neurofascin, Nfasc155 in glia and Nfasc186 in neurons, are required for the assembly of these sp...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2020
ISSN: 0960-9822
DOI: 10.1016/j.cub.2020.02.037